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Antivert

Antivert User Reviews >>

 

Drug Description

Antivert Drug Description

 

ANTIVERT®
(meclizine HCl) Tablets/12.5 mg

ANTIVERT®/25
(meclizine HCl) Tablets/25 mg

ANTIVERT®/50
(meclizine HCl) Tablets/50 mg

DRUG DESCRIPTION

What are the possible side effects of meclizine (Antivert, Bonine, Dramamine II, D-Vert)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects may include:

  • blurred vision;
  • dry mouth;
  • constipation; or
  • dizziness, drowsiness.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side…

Read All Potential Side Effects and See Pictures of Antivert »

Chemically, Antivert® (meclizine HCl) is 1-(p-chloro-α-phenylbenzyl)-4-(m-methylbenzyl) piperazine dihydrochloride monohydrate.

 

Inert ingredients for the tablets are: dibasic calcium phosphate; magnesium stearate; polyethylene glycol; starch; sucrose. The 12.5 mg tablets also contain: Blue 1. The 25 mg tablets also contain: Yellow 6 Lake; Yellow 10 Lake. The 50 mg tablets also contain: Blue 1 Lake; Yellow 10 Lake

INDICATIONS

Based on a review of this drug by the National Academy of Sciences – National Research Council and/or other information, FDA has classified the indications as follows:

Effective: Management of nausea and vomiting, and dizziness associated with motion sickness.

Possibly Effective: Management of vertigo associated with diseases affecting the vestibular system.

Final classification of the less than effective indications requires further investigation.

DOSAGE AND ADMINISTRATION

Vertigo

For the control of vertigo associated with diseases affecting the vestibular system, the recommended dose is 25 to 100 mg daily, in divided dosage, depending upon clinical response.

Motion Sickness

The initial dose of 25 to 50 mg of Antivert should be taken one hour prior to embarkation for protection against motion sickness. Thereafter, the dose may be repeated every 24 hours for the duration of the journey.

HOW SUPPLIED

Antivert®—12.5 mg tablets:

Bottles of 100
(NDC 0662-2100-66),
(NDC 0049-2100-66)

Bottles of 1000
(NDC 0662-2100-82),
(NDC 0049-2100-82)

Antivert®/25—25 mg tablets:

Bottles of 100
(NDC 0662-2110-66),
(NDC 0049-2110-66)

Bottles of 1000
(NDC 0662-2110-82),
(NDC 0049-2110-82)

Antivert®/50—50 mg tablets:

Bottles of 100
(NDC 0662-2140-66),
(NDC 0049-2140-66)

Antivert Side Effects & Drug Interactions

 

SIDE EFFECTS

Drowsiness, dry mouth and, on rare occasions, blurred vision have been reported.

Antivert Warnings & Precautions

 

WARNINGS

Since drowsiness may, on occasion, occur with use of this drug, patients should be warned of this possibility and cautioned against driving a car or operating dangerous machinery.

Patients should avoid alcoholic beverages while taking this drug.

Due to its potential anticholinergic action, this drug should be used with caution in patients with asthma, glaucoma, or enlargement of the prostate gland.

Usage in Children

Clinical studies establishing safety and effectiveness in children have not been done; therefore, usage is not recommended in children under 12 years of age.

Usage in Pregnancy

Pregnancy Category B.Reproduction studies in rats have shown cleft palates at 25-50 times the human dose. Epidemiological studies in pregnant women, however, do not indicate that meclizine increases the risk of abnormalities when administered during pregnancy. Despite the animal findings, it would appear that the possibility of fetal harm is remote. Nevertheless, meclizine, or any other medication, should be used during pregnancy only if clearly necessary

Antivert Clinical Pharmacology

 

CLINICAL PHARMACOLOGY

Actions

Antivert is an antihistamine which shows marked protective activity against nebulized histamine and lethal doses of intravenously injected histamine in guinea pigs. It has a marked effect in blocking the vasodepressor response to histamine, but only a slight blocking action against acetylcholine. Its activity is relatively weak in inhibiting the spasmogenic action of histamine on isolated guinea pig ileum.

Antivert Consumer

IMPORTANT NOTE: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your health care professional. Always seek the advice of your health care professional if you have any questions about this product or your medical condition. This information is not intended as individual medical advice and does not substitute for the knowledge and judgment of your health care professional. This information does not contain any assurances that this product is safe, effective, or appropriate for you.

MECLIZINE – ORAL

(MECK-lih-zeen)

COMMON BRAND NAME(S): Antivert, D-vert, Dramamine II, Univert, Vertin

USES: Meclizine is an antihistamine that is used to prevent or treat nausea, vomiting, and dizziness caused by motion sickness. It may also be used to reduce lightheadedness, dizziness, and loss of balance (vertigo) caused by diseases that affect the inner ear.

HOW TO USE: Take this medication by mouth with or without food, or as directed by your doctor. To prevent motion sickness, take the first dose one hour before starting an activity such as travel. You may take another dose every 24 hours if needed. Chewable tablets must be chewed thoroughly before swallowing.

Follow the directions on the label, or take as directed by your doctor. Do not take more medication than recommended. Ask your doctor or pharmacist if you have questions.

For control of vertigo and other conditions, take as directed by your doctor. Your dosage is based on your medical condition and response to therapy.

Inform your doctor if your condition does not improve or if it worsens

Antivert Consumer (continued)

SIDE EFFECTS: Drowsiness, dry mouth, and tiredness may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Some patients, particularly children, may experience excitability rather than drowsiness.

If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur: vision changes, decreased/painful urination, seizures.

A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US –

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before taking meclizine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: breathing problems (e.g., asthma, emphysema), glaucoma, prostate problems, seizure disorder.

This drug may make you drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages.

Caution is advised when using this drug in the elderly because they may be more sensitive to its effects, especially drowsiness.

This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.

This drug may pass into breast milk and could have undesirable effects on a nursing infant. Therefore, breast-feeding is not recommended while using this medication. Consult your doctor before breast-feeding

DRUG INTERACTIONS: Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop or change the dosage of any medicine before checking with them first.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: antispasmodics (e.g., atropine, belladonna alkaloids), drugs for Parkinson's disease (e.g., anticholinergics such as benztropine, trihexyphenidyl), scopolamine, tricyclic antidepressants (e.g., amitriptyline).

Tell your doctor or pharmacist if you also take drugs that cause drowsiness, such as certain antihistamines (e.g., diphenhydramine), anti-seizure drugs (e.g., carbamazepine), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., chlorpromazine, risperidone, trazodone).

Check the labels on all your medicines (e.g., cough-and-cold medicines, allergy products) because they may contain antihistamines (e.g., chlorpheniramine) or other ingredients that could cause drowsiness. Ask your pharmacist about the safe use of those products.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include: mental/mood changes, extreme drowsiness, loss of consciousness, seizures.

NOTES: Do not share this medication with others.

MISSED DOSE: If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

STORAGE: Store at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture. Brief storage up to 104 degrees F (40 degrees C) is permitted. Do not store in the bathroom. Keep all medicines away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

Antivert Patient Information Including Side Effects

Brand Names: Antivert, Bonine, Dramamine II, D-Vert

Generic Name: meclizine (Pronunciation: MEK li zeen)

  • What is meclizine (Antivert)?
  • What are the possible side effects of meclizine (Antivert)?
  • What is the most important information I should know about meclizine (Antivert)?
  • What should I discuss with my healthcare provider before taking meclizine (Antivert)?
  • How should I take meclizine (Antivert)?
  • What happens if I miss a dose (Antivert)?
  • What happens if I overdose (Antivert)?
  • What should I avoid while taking meclizine (Antivert)?
  • What other drugs will affect meclizine (Antivert)?
  • Where can I get more information?

What is meclizine (Antivert)?

Meclizine is an antihistamine that reduces the natural chemical histamine in the body.

Meclizine is used to treat or prevent nausea, vomiting, and dizziness caused by motion sickness. Meclizine is also used to treat symptoms of vertigo.

Meclizine may also be used for other purposes not listed in this medication guide.

Antivert 12.5 mg

 

oblong, blue/white, imprinted with 210, ANTIVERT

Antivert 25 mg

 

oblong, white/yellow, imprinted with 211, ANTIVERT

Antivert 50 mg

 

oblong, blue/yellow, imprinted with 214, ANTIVERT

Meclizine 12.5 mg-GG

 

oval, blue, imprinted with GG 141

Meclizine 12.5 mg-PAR

 

elliptical, blue/white, imprinted with par, 034

Meclizine 25 mg-GG

 

oval, yellow, imprinted with GG 261

Meclizine 25 mg-PAR

 

elliptical, white/yellow, imprinted with par, 035

Meclizine 25 mg-WAT

 

oval, white/yellow, imprinted with WATSON 803

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What are the possible side effects of meclizine (Antivert)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects may include:

  • blurred vision;
  • dry mouth;
  • constipation; or
  • dizziness, drowsiness.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about meclizine (Antivert)?

Use this medication exactly as directed on the label, or as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended.

You should not take this medication if you are allergic to meclizine.

Before taking meclizine, tell your doctor if you have asthma or other breathing disorder, glaucoma, an enlarged prostate, or problems with urination.

Do not give this medication to a child younger than 12 years old.

Meclizine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol. It can increase some of the side effects of meclizine.

Cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by meclizine. Avoid taking these other medications at the same time you take meclizine

Antivert Patient Information including How Should I Take

In this Article

  • What is meclizine (Antivert)?
  • What are the possible side effects of meclizine (Antivert)?
  • What is the most important information I should know about meclizine (Antivert)?
  • What should I discuss with my healthcare provider before taking meclizine (Antivert)?
  • How should I take meclizine (Antivert)?
  • What happens if I miss a dose (Antivert)?
  • What happens if I overdose (Antivert)?
  • What should I avoid while taking meclizine (Antivert)?
  • What other drugs will affect meclizine (Antivert)?
  • Where can I get more information?

 

What should I discuss with my healthcare provider before taking meclizine (Antivert)?

You should not take this medication if you are allergic to meclizine.

Before taking meclizine, tell your doctor if you are allergic to any drugs, or if you have:

  • asthma or other breathing disorder;
  • glaucoma;
  • an enlarged prostate; or
  • problems with urination.

If you have any of these conditions, you may not be able to use this medication, or you may need a dose adjustment or special tests during treatment.

FDA pregnancy category B. Meclizine is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether meclizine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Do not give this medication to a child younger than 12 years old.

How should I take meclizine (Antivert)?

Use this medication exactly as directed on the label, or as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended.

Take meclizine with a full glass of water.

The chewable tablet may be swallowed whole, crushed, or chewed.

To prevent motion sickness, take meclizine about 1 hour before you travel or engage in activity that causes motion sickness. You may take meclizine once every 24 hours while you are traveling, to further prevent motion sickness.

To treat vertigo, you may need to take meclizine several times daily. Follow your doctor’s instructions.

Meclizine can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.

Store meclizine at room temperature away from moisture, heat, and light

Antivert Patient Information including If I Miss a Dose

In this Article

  • What is meclizine (Antivert)?
  • What are the possible side effects of meclizine (Antivert)?
  • What is the most important information I should know about meclizine (Antivert)?
  • What should I discuss with my healthcare provider before taking meclizine (Antivert)?
  • How should I take meclizine (Antivert)?
  • What happens if I miss a dose (Antivert)?
  • What happens if I overdose (Antivert)?
  • What should I avoid while taking meclizine (Antivert)?
  • What other drugs will affect meclizine (Antivert)?
  • Where can I get more information?

 

What happens if I miss a dose (Antivert)?

Since meclizine is sometimes taken only when needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose (Antivert)?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include extreme drowsiness.

What should I avoid while taking meclizine (Antivert)?

Meclizine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol. It can increase some of the side effects of meclizine.

Cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by meclizine. Avoid taking these other medications at the same time you take meclizine.

What other drugs will affect meclizine (Antivert)?

There may be other drugs that can interact with meclizine. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about meclizine.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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